Quinolines and derivatives
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Filtered Search Results
Ambeed R 4Benzyl2oxazolidinone
(R)-4-Benzyl-2-oxazolidinone, 102029-44-7, 98%
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Medchemexpress LLC 3,6,9,12,15,18-Hexaoxanonadecan-1-amine | 184357-46-8 | ≥97.0% | 10 G
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m-PEG6-Amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, while ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
- PEG-based PROTAC linker
- Cleavable ADC linker
- Used in the synthesis of PROTACs
- Used in the synthesis of antibody-drug conjugates (ADCs)
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Medchemexpress LLC 5(6)-Carboxy-2',7'-dichlorofluorescein | 111843-78-8 | 99.0% | 100 MG
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5(6)-Carboxy-2',7'-dichlorofluorescein is an ideal substrate for MRP2 vesicular transport assay, possessing excellent detection and transport properties.
- Ideal substrate for MRP2 vesicular transport assay
- Excellent detection and transport properties
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Medchemexpress LLC mPEG-amine (MW 10000) | 80506-64-5 | 637448 | 98.0% | (C2H4O)nC3H9NO | 100 MG
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mPEG-amine (MW 10000), also known as mPEG-NH2 (MW 10000), is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Enables selective protein degradation
Average molecular weight of 10000
Appears as a white to off-white solid
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000285818 QUINIDINE METHIODIDE 10MG
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Ambeed 4Amino2bromopyrimidine
4-Amino-2-bromopyrimidine, 1160994-71-7, 95%
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Ambeed 1Methyl4piperidinemethanol
1-Methyl-4-piperidinemethanol, 20691-89-8, 97%
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Medchemexpress LLC M-PEG12-amine | 1977493-48-3 | MFCD00131599 | ≥98.0% | 559.69 g/mol | C25H53NO12 | 100 MG
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m-PEG12-amine is a methoxy-terminated polyethylene glycol linker containing a 12-unit PEG chain and a terminal primary amine. It serves as a flexible, non-cleavable spacer for conjugation chemistry in linker and ADC/PROTAC synthesis.
- Methoxy-terminated PEG chain, 12 units.
- Terminal primary amine suitable for amide or carbamate coupling.
- Molecular weight approximately 559.7 g/mol; formula C25H53NO12.
- High purity (≥98%) appropriate for research and synthesis workflows.
- Supplied in small-scale quantities suitable for laboratory use.
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Medchemexpress LLC 3,6,9,12,15,18-hexaoxanonadecan-1-amine | 184357-46-8 | 97.0% | 295.37 g/mol | C13H29NO6 | 100 MG
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m-PEG6-Amine is a methoxy-terminated PEG6 linker bearing a primary amine; it is used as a spacer and conjugation handle in PROTAC and antibody-drug conjugate (ADC) synthesis. The compound has formula C13H29NO6, molecular weight 295.37 g/mol, and is supplied at ~97.0% purity for research use.
- PEG6 spacer with methoxy terminus and primary amine for conjugation
- Suitable for PROTAC linker and ADC linker synthesis
- Hydrophilic polyethylene glycol chain improves solubility and flexibility
- Available in multiple pack sizes, including 100 MG
- Provided at research-grade purity for synthetic applications
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Medchemexpress LLC Sulfo-SPP | 452072-27-4 | 97.1% | 420.48 g·mol⁻1 | C14H16N2O7S3 | 5 MG
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Sulfo-SPP is a heterobifunctional, thiol-cleavable, membrane-impermeable crosslinker used as an ADC linker in bioconjugation research. It reacts selectively with primary amines and contains a cleavable disulfide linkage that enables release under reducing conditions. Supplied for research use only.
- Heterobifunctional thiol-cleavable crosslinker.
- Membrane impermeable sulfonate group improves aqueous solubility.
- Cleavable disulfide linkage for controlled release under reducing conditions.
- Suitable for antibody-drug conjugate and bioconjugation applications.
- Available in small pack sizes for research use.
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568208 AZASETRON-HCL-200MG
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Ambeed Methyl 1bromocyclopropanecarbo
Methyl 1-bromocyclopropanecarboxylate, 96999-01-8, 97%
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Medchemexpress LLC Chlorprothixene (hydrochloride) | 6469-93-8 | 99.9% | 200 MG
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Chlorprothixene is a dopamine and histamine receptor antagonist known for its antipsychotic activity. It exhibits high affinity for various human dopamine and histamine receptors.
- Antagonizes human D1, D2, D3, D5, and H1 receptors with low nanomolar Ki values.
- Inhibits 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 in HEK293 cells.
- Antagonizes H1 receptor activity in human HeLa cells.
- Binds to 5-HT7, 5-HT6, and 5-HT2 receptors with high pKi values.
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Sigma Aldrich Fine Chemicals Biosciences 8-Hydroxy-2-quinolinecarboxylic acid >=98.0% (HPLC) | 1571-30-8 | MFCD00168972 | 1G
8-Hydroxy-2-quinolinecarboxylic acid >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | Mol Wt: 189.17 | 1571-30-8 | MFCD00168972 | 1G
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Sigma Aldrich Fine Chemicals Biosciences Quinacrine dihydrochloride >=90% | 69-05-6 | MFCD00012659 | 100G
Quinacrine dihydrochloride >=90% | Purity: >=90% | Mol Wt: 472.88 | 69-05-6 | MFCD00012659 | 100G
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